xTAG® Gastrointestinal Pathogen Panel (xTAG GPP)

Globally, there are an estimated two billion cases of diarrheal symptoms every year. Due to similar symptoms virus, parasite and bacteria, a comprehensive diagnostic is difficult. xTAG GPP is a qualitative multiplex diarrhea test that helps molecular biologists and microbiologists with the simultaneous detection and identification of gastrointestinal pathogens. The assay uses Luminex xTAG Technology and the xMAP® Technology platform detect multiple infectious agents in a single sample.

Transforming diarrhea diagnostics

xTAG GPP is the first GI diagnostic to offer 15 major infectious organisms in a single test. It can detect Hospital Acquired Infections (HAI) such as C. difficile or Norovirus, foodborne illness agents like E. Coli or Salmonella and common pediatric diarrhea. For more information visit our xTAG® GPP webpage.

Multiplexed molecular testing for a reliable, actionable result in under 5 hours

Gastroenterologist

Get more results per test than any other method, in time to affect patient care

MethodTests ForTurn-Around TimeDiagnostic Yield
Stool cultureSingle bacterial pathogen per test2–3 daysUp to 6%2
Ova and parasite (O&P) examParasitic pathogensSeveral days – sample must be collected over 3 daysUp to 3%3,4
Rapid testsSingle pathogen per test20–30 minVaries
Real-time PCR1–3 pathogens per testUnder 5 hoursVaries; depends on the pathogen target, individual performance and number of assays
ELISASingle antigen/antibody per test6–24 hoursVaries
xTAG GPPUp to 14 bacterial, viral, and parasitic pathogens in a single testUnder 5 hours (Including extraction steps)30%

Pinpoint the cause of gastrointestinal infections quickly and efficiently

Enable timely, informed treatment decisions for all diarrhea patients

Get answers you can rely on with a validated, sensitive and specific assay

xTAG GPP - Excellent sensitivity and specificity performance for all targets5

assessed with MAGPIX

Target (Analyte)SensitivitySpecificity
Salmonella84.6%98.4%
Shigella97.7%97.8%
Campylobacter97.5%97.8%
Yersinia enterocoliticaN/A*100%
Enterotoxigenic E. coli (ETEC) LT/STN/A*97%
E. coli O15794.1%98.8%
Shiga-like Toxin producing E. coli (STEC) stx 1/stx 2100%98.6%
Clostridium difficile Toxin A/B97.7%94.9%
Vibrio choleraeN/A*100%
  
Adenovirus 40/41100%100%
Rotavirus A94.7%99.8%
Norovirus GI/GII93.5%96.4%
  
Giardia lamblia100%97.5%
Cryptosporidium91.7%99.9%
Entamoeba histolytica100%98.8%

*Due to low sample size, clinical sensitivity was not assessed for ETEC, Yersinia enterocolitica and Vibrio cholerae. However, analytical accuracy for these analytes was demonstrated in the limit of detection and reactivity studies with cultural isolates or plasmids.

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Want to know more about Gastrointestinal Pathogen Panel? Join us at Planet xMAP Europe 2012 to discover the many ways in which xMAP technology and xTag Technology are enabling scientists and researchers to perform multiplexed assays.

References: 1. CDC, National Center for Zoonotic, Vector-borne and Enteric Diseases. 2. Slutsker L et al. Annals of Internal Medicine 1997; 126(7):505–513. 3. Fotedar R et al. Journal of Clinical Microbiology 2007; 45(3):1035–1037. 4. Tuncay S et al. Türkiye Parazitoloji Dersigi 2007; 31(3):188–193. 5. Luminex Corporation. xTAG® Gastrointestinal Pathogen Panel (GPP) Package Insert.

For In Vitro Diagnostic Use. Products are region specific and may not be approved in some countries/regions. Please contact Luminex at support@luminexcorp.com to obtain the appropriate product information for your country of residence.

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Gastrointestinal Pathogen Panel

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